The easiest and in my opinion most efficient farming place is nihlathak.
An average run with decent amount of magic find will give you:
1-5 tiered uniques
0-3 sacred uniques
0-3 set items
On realm i did about 100 sigs an hour with cubing random su and sets to sigs. On singleplayer the player x command enhances this place by far. Depending on your build i demand to clear the whole nihlathak area. The time/drop ratio is by far better than farming teganze, dunc, k3k, ta or fauzt.
Second best place is ta. Well with endgame equip and the right build this can change, but as soon farming any place is hard it makes it slow and not really regarding. The higher drop ratio does not equilize the time you need for it. At the end the time/drop ratio is the only thing that counts. Do any farming place for maybe 2 hours, count the drops (sigs, su, tu, sets, great runes), calculate the average drop per hour and see what is the best place for your char/build to farm.