The TLDR 2H Barb

Mystic orbs: Weapon: %enhanced damage, AR, mana on atttack; Armors: %enhanced defense, FHR, all resists, dex/vit
Sockets: weapon - JAH, chest if TU - JAH, rest: MAL/GUL/LO/PUL for resists, SHA - IAS, LEM - EXP, LAH - 3% all stat (strongest)

Nerfs are coming boys

red: affects our build

Nerfs:
Thunderfury is now a 25% chance to proc instead of 50%.
Fixed a bug where unique Barbarian two-handed Axes had double innate chances.
Replaced the "-X% target defence" and "-X monster defence per hit" affixes on items which had them. (big nerf, rip visegrip)
CHANGES TO PARTY BUFFS: such as bloodlust, motw etc - nerfs
THUNDERSLAM: 15s cd (from 4s)
ANCIENT BLOOD: now gives 0.5% max life per skill level, down from 1%
DEATH GAZE: weapon damage decreased by 10%
LION STANCE: Magic Damage -19%, fixed a bug which made this skill give more damage than intended, 10% less damage per slvl
EAGLE STANCE: life regeneration rate has been halved
TITAN STRIKE: healing removed
SPIRIT GUIDE: aura is now only carried by wolves and not Ancient Spirits + nerfed EWD per slvl to 4% (from 15?)
SPIRIT WALK: minimum cooldown is now 3 seconds
SCREAMING EAGLE: no longer reduces enemy attack speed
NEPHALEM SPIRIT: removed cold damage, adjusted fire/lightning, total damage nerf 20%

Buffs:
iron spiral +10% dmg
wolf stance +10% ewd per slvl, now 15% per slvl total (good buff)

Nerf nerf nerf why nerf so much

They hate fun.
No but its still viable.

I'd change skill tree now, try to use that juicy wolf stance buff.
Bear version can still work but with all those nerfs, visegrip nerf, our damage will drop pretty hard, to the point its gonna be annoying to kill lategame bosses.

I'd go something like this:

Few points about this tree:
- go around anc blood nerf by getting not-nerfed daedalus, and some AR (much needed after visegrip nerf)
- get buffed wolf stance, increase trash kill speed with free cb and pretty decent ewd
- defense comes from spirit guide (defense part isnt nerfed, 15tcd per base level)
- don't go all in on wolves max level (no ancient blood) because there is not enough points and their damage bonus is less important with wolf stance ewd
- skip fortress = not enough points, respec if you can't kill kabraxis as melee
- gain windform to travel through stuff, makes bunch of ubers way easier
- get %physical resistance from gear, won't be 50% but we can hit about 35. In many instances we can still use 1pt bear for 50%.
- not skip Shower of Rocks, good in dense places, tagging bosses to reduce their speed/hit chance, underrated skill.
- still use thunderslam, just every 15s not 4s.. now you can truly see how goot it was
- we still go 2h axe, even with proc nerfed, average damage is still so good compared to swords, wouldn't give it up
- deathgaze is nerfed to 55%, almost the same, still miles better than iron spiral in early-mid game
- healer specs work the same but will be worse, so stuff you used them for will be bit harder
- wolf stance speed is best utilized with 2h axe, because that 280 ias requirement, so we can get full value from it, unlike if we go thrower or dual wielder which requires very little ias to cap speed, thus making that part of wolf stance going to waste
- we get more lah runes in gear as we don't need ias/fhr with wolf stance, we get total char def upgrade on armor to boost defense even furher

edit:
updated first post

feel free discuss changes

Im gonna look into the endgame (lvl 135+) version with the changes, with possible gg/BIS gear.

Normally candlewake was BIS, might no longer be the case. SBS? Marchosias chest?
Visegrips ==> ??? for endgame

Im considering honorifics with abandon blessing for BIS gear on gloves. Not sure about boots and belt (akarats and marchosias a.t.m.).

I don't think you wanna go honorific over craft, you miss out on AR crafted roll and juicy all stats/life from craft, it isn't worth double mo, unless you go some specifc umo project.
AR needs to be on more items, for example 4x EARTH runeword boots looks pretty good.

Endgame is bit different because you might just straight up outstat everything that you can get away with very little physical resistance, then you go full dps armors. Otherwise you must get pieces with high %physical res, which is 16% from erawan. Khazra plate seems to be there, hard to beat this chest, even with demon blood aura affecting only owner not his minions/party.

what would be enough AR? 30k? 50k?

For endgame ubers depends on which one, i'd say around 30-40k, for bosses more, for boss like samael much more, which is big damage nerf to that specific spec. But if you get bunch of +all stat items, AR rolls here and there, most charms, you should get there.
Just we need to count that this build will deal certain % less damage to bosses than dexterity wdm build that runs over 100k ar without any effort.

Love this guide, great job! Sorry to ask but, what is the difference between crafted weps, shrine weps, and TU's? I'm just iffy on the crafted weapon part.

Craft gets way more damage, you can roll up to +375 maximum. Compare that to TU labrys.
Shrine you use doesn't matter in getting that mod, it gives other bonus stats.