Well, it depends on a few factors:
1. if you have some cool reanimates from Harkon Gem and Fool's Gold (Destroyer Shaman, Unseelie Lady, Pit/Moon Knight), I don't recommend wearing Sepultura. Otherwise, it's a pretty good helm, esp. with its high %DR.
2. If you lack %life leech (like 75 or less), I would equip Lionblood's Crest.
3. If you don't equip any perfect gems for max resists, you should think about
Witchhunter's Hood
Witchhunter's Hood
Cap (Sacred)
Defense: (2136 - 2611) to (2161 - 2642)
Required Level: 90
Required Strength: 250
Item Level: 1
+(80 to 120)% Enhanced Defense
10% to Strength
10% to Dexterity
Maximum Elemental Resists +2%
Elemental Resists +(31 to 40)%
Physical Resist 5%
(16 to 20)% Bonus to Defense
Requirements -50%
Socketed (4)
Witchhunter's Attire
(Assassin Claw Set)
. You can wear this if you don't have upg. Kabraxis charm yet, for example. It also has very good stats.