Perhaps regarding RNG spawned items, however Astrogha's Moon set is the perfect set for any poison based subclass, melee, missile, or spell and I doubt anyone would disput that. On my Snake Stance WW barb, killing bosses can be a real pain when they are timer based and I'm waiting for the poison to "do it's thing" but fail the quest despite 100K poison damage due to length of time it takes for boss man to die to poison. Using Wyrd in conjunction with my Snake Stance WW would be amazing and frankly, it (this set) seems literally designed for this combination, however it seems oversight made Wyrd unusable for melee in this instance. IDK, maybe it is a "feature" that melee based builds are unable to use Wyrd, but it is a shame.