I think the important rolls on a 2h weapon is proc, high max damage and some minor ed (50% allows you to cap with MOs only due to crafts getting twice the effect from MO) but the most important affix is a high max damage roll and then some decent proc of some sort.
Weirds dont guarantee a high max damage roll by any means so you might as well roll with creepys if possible for the free str.

I rolled this weapon earlier today and even though it doesn't have a proc I think it is worth testing, holy lance requires 133% attack speed to reach 8fpa in dragonform which is (very) realistic without overdoing it, 259 for 7fpa sounds like a struggle though (I do have 18 sockets that could theoretically hold 10-15% as Ber jewels) but that is just horrible to roll (and I'll lose %-str on doing it most likely)
I have been running TA with this weapon:

which worked fine at 8fpa except for the single target
I think you can use some shimmering crafts too if you want for better plague but generally creepy is your shrine of choice - you can in theory use almost any shrine if you really want to but it wont be optimal because you'll "waste" affixes on the fixed ones from a bad shrine.