So I managed to get sweetFX to work for Diablo II - a 3rd party program that changes the colors of the game. Here are some (extreme) examples
http://imgur.com/a/ueChyIt's mostly useful for either color correcting, sharpness, or creating some sort of hue/tone to the game for screenshots or videos. It's a pain to play with it normally if you play it with extreme color settings like I did in the screenshots, because it will be difficult to determine between rares and uniques. If you guys are interested I can make a quick guide on how to set it up.
Heres a more tame setup with much more readable item names
Before:

After:
