As for why a program needs admin rights:
► Show Spoiler
(source: https://www.symantec.com/connect/blogs/ ... tor-rights Took me 10 seconds to google)
I guess the reason is point 5 in case of fan-created tools (Heck, it's even the case for diablo 2 itself). Anyway, you're right to be sceptical about programs you don't know anything about, that's why I usully wait for people to try out new tools before I use them. D2 clicker and d2qol have been around for quite some time already and there is no reason to be concerned, else the modders would've taken counter-measures as in closing the threads and taking them down from the tools list (d2clicker is in it at least). Never tried out d2qol, so I can't say anything about it, but d2clicker definitely doesn't contain any viruses or anything of that sort.